A Journal of Cognitive Neuroscience study was described as a "wake-up call" about the impact of social deprivation.
Normal nine and 10-year-olds from rich and poor backgrounds had differing electrical activity in a part of the brain linked to problem solving. The brains of children from low-income families process information differently to those of their wealthier counterparts.
Since the children were, in health terms, normal in every way, the researchers suspected that "stressful environments" created by low socioeconomic status might be to blame.
Dr Mark Kishiyama, one of the researchers, said: "The low socioeconomic kids were not detecting or processing the visual stimuli as well - they were not getting that extra boost from the prefrontal cortex."
Previous studies have suggested that children in low-income families are spoken to far less - on average hearing 30 million fewer words by the age of four.
Professor Robert Knight, added: "This is a wake-up call - it's not just that these kids are poor and more likely to have health problems, but they might actually not be getting full brain development from the stressful and relatively impoverished environment associated with low socioeconomic status."
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